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Lucy Zumwinkle Kornblith, M.D., FACS

Lucy Zumwinkle Kornblith, M.D., FACS

  • Associate Professor of Surgery
  • Division of General Surgery
  • Trauma and Surgical Critical Care
  • Zuckerberg San Francisco General Hospital
  • The Director of Gender Equity
  • Co-chair, Muriel Steele Society

Contact Information

415-206-4627
[email protected]
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University of California Santa Barbara, Santa Barbara, CA; BS, Biological Sciences, 2005

University of Colorado, Denver, CO; MD, 2009

University of California, San Francisco, CA 2019, Diversity, Equity, and Inclusion Champion Training

  • University of California San Francisco, General Surgery Residency, 2016
  • UCSF, Surgical Critical Care and Trauma Surgery, 2016-17
  • UCSF, Trauma & Emergency Care, 2017-18
  • American Board of Surgery, Surgery
  • American Board of Surgery, Surgical Critical Care
  • Acute Care Surgery
  • General Surgery
  • Surgical Critical Care
  • Trauma Surgery
  • Acute Traumatic Coagulopathy
  • Functional Coagulation
  • Lung Injury
  • Platelets
  • Tracheostomy
  • Transfusion
  • Whole Blood

Lucy Zumwinkle Kornblith, M.D., F.A.C.S. received her undergraduate degree from University of California Santa Barbara, her M.D. from the University of Colorado, completed her General Surgery residency at the University of California San Francisco (UCSF), a Trauma and Critical Care Clinical Translational Research Fellowship at UCSF, and subspecialty training in Trauma and Acute Care Surgery and Surgical Critical Care at UCSF prior to joining the faculty at UCSF.

She clinically practices Trauma Surgery, Acute Care Surgery, and Surgical Critical Care. She has played a pivotal role in the translational study of blood system failure after injury, centrally focused on post-injury platelet biology. Her research program is multi-pronged, covering 1) Translational research to identify novel biology of blood system failure through the lens of platelets, 2) Large observational studies to identify predictors of bad outcomes after injury, and 3) Clinical trials investigating therapeutics and resuscitation strategies for injured patients. Her research program has been funded by the National Institutes of Health, the Department of Defense, the American College of Surgeons, the Eastern Association for the Surgery of Trauma, the UCSF School of Medicine Irene Perstein Award, and the Doris Duke Charitable Foundation. Dr. Kornblith is the Department of Surgery Director of Gender Equity and a co-chair of the UCSF Department of Surgery Muriel Steele Society, an inclusive community dedicated to inspiring, supporting, and promoting 400+ women surgeons so they can thrive at all stages of their careers.

  Award  
  Confired By    
  Date    
  • George H. A. Clowes Jr., MD, FACS, Memorial Research Career Development Award
  • The American College of Surgeons
  • 2023 - 2028
  • Reviewer of the month; The Journal of Trauma and Acute Care Surgery
  • The American Association for the Surgery of Trauma
  • 2023
  • UCSF Holly Smith Award for Exceptional Service to the School of Medicine
  • University of California San Francisco
  • 2023
  • 40 under 40 female surgeons, The Association of Women Surgeons
  • The American Association for the Surgery of Trauma
  • 2022
  • Canizaro Award, The American Association for the Surgery of Trauma
  • The American Association for the Surgery of Trauma
  • 2021
  • Editor's Choice, The Journal of Trauma and Acute Care Surgery
  • The Journal of Trauma and Acute Care Surgery
  • 2021
  • UCSF Clinical and Translational Science Institute Mentor of the Year
  • University of California San Francisco
  • 2021
  • Department of Surgery Muriel Steele Society Influential Women in Surgery Honor Roll
  • University of California San Francisco
  • 2019 - 2022
  • Irene Perstein Award
  • University of California San Francisco
  • 2019
  • Department of Surgery Muriel Steele Society Influential Women
  • University of California San Francisco
  • 2019
  • Department of Surgery Robert C Lim Jr. MD & Arthur N Thomas M
  • University of California San Francisco
  • 2019
  • Trauma Research Scholarship
  • Eastern Association for the Surgery of Trauma
  • 2018
  • Excellence in Research Award
  • Surgical Critical Care Program Directors Society Board of Directors
  • 2017
  • Fred H. & Esther E. Nusz Resident Achievement Award
  • University of California San Francisco
  • 2016
  • Haile T. Debas Resident Teaching Award
  • University of California San Francisco
  • 2016
  • Earl G Young First Place Winner
  • Western Trauma Association
  • 2014
  • Dr. Kornblith is a mentor for a diverse learner pool. Her mentees are in pursuit of academic scientific agendas across various points in their careers, various specialties, and various institutions (including other University of California campuses). She works with undergraduate students from various universities to learn important activities of translational research including data collection via chart review, clotting assays, plasma organization, transport of biospecimens, and laboratory clerical activities. She serves as a mentor for UCSF medical students in the UCSF School of Medicine Deep Explore program and Clinical Microsystems Course, and has UCSF medical students in her laboratory. She is a designated clinical and research advisor to residents in the UCSF Department of Surgery. Dr. Kornblith was awarded the 2021 UCSF CTSI Mentor of the Year Award. In addition. Dr. Kornblith mentors beyond UCSF via participating on Thesis Statement Review Committees and dissertation committees at the University of California, Berkeley. In addition, Dr. Kornblith mentors in the San Francisco BUILD Student Training program which is an NIH-funded pipeline/pathway program support historically underrepresented undergraduate students from San Francisco State University to pursue graduate study (PhD, MD-PhD, or Masters) in the biomedical sciences.

    Available to Mentor as: (Review Mentor Role Definitions):    · Career Mentor    · Co-Mentor    · Lead Research / Scholarly Mentor    · Project Mentor
    Contact for Mentoring:
    •    · Email (see above)

    Learn about the Faculty Mentoring Program and the CTSI Mentor Development Program

     

    Dr. Kornblith is a surgeon scientist focused on translational studies in the field of Trauma with a particular interest in elucidating the mechanisms and mediators of trauma-induced coagulopathy and resuscitation techniques for post-traumatic hemorrhage. She has essential research experience studying post-injury platelet biology and technical expertise in functional laboratory measures of coagulation. She has extensive experience and expertise in the nuances of biospecimen collection in severely injured patients. She is trained in clinical research design and biostatistics from the Clinical and Translational Science Institute at UCSF. She is funded by the National Institutes of Health, the Department of Defense, the American College of Surgeons, the Eastern Association for the Surgery of Trauma, the UCSF School of Medicine Irene Perstein Award, and the Doris Duke Chartiable Foundation. She collaborates cross-disciplinary and multi-institutionally to advance knowledge within her field of interest.

    I am interested in:
    • Academic Collaboration
    • Academic Senate Committee Service
    • Multicenter Clinical Research
    • Community and Stakeholder Organizations
    • Companies and Entrepreneurs
    • Press
    • Prospective Donors
    • Physician-Scientist



    Data provided by UCSF Profiles, powered by CTSI
    ORCID iD: 0000-0002-1861-9691 Additional info
    • The Platelet Transcriptome and Organ Failure After Injury: Discovering Molecular Biomarkers and Preventative Targets through Interrogating Novel RNA Modifications
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      Sep 2023
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      Aug 2028
      Principal Investigator
    • Platelet Biology: Mechanisms and Outcomes
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      Jul 2023
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      Jun 2028
      Principal Investigator
    • Post-Injury Platelet Biology: Mechanisms and Outcomes
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      Sep 2018
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      Aug 2023
      Principal Investigator
    • Freeze Dried Platelet Extracellular Vesicles as a Hemostatic Adjunct to Resuscitation for Prolonged Field Care
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      Jul 2020
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      Jun 2022
      Co-Investigator
    • The ACCT Study: Assessing COVID-19 Associated Coagulopathy and Thrombosis
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      Jun 2020
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      May 2021
      Primary Investigator
    • Post-Injury Platelet Genomics
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      Aug 2019
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      Jul 2020
      Primary Investigator
    • Post-Injury Platelet Function
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      Aug 2018
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      Jul 2019
      Principal Investigator
    Data provided by UCSF Profiles, powered by CTSI
    MOST RECENT PUBLICATIONS FROM A TOTAL OF 136
    Data provided by UCSF Profiles, powered by CTSI
    1. Abella M, Hayashi J, Martinez B, Inouye M, Rosander A, Kornblith L, Elkbuli A. A National Analysis of Racial and Sex Disparities Among Interhospital Transfers for Emergency General Surgery Patients and Associated Outcomes. J Surg Res. 2023 Nov 01; 294:228-239. View in PubMed
    2. Cuschieri J, Kornblith L, Pati S, Piliponsky A. The Injured Monocyte: The Link to Chronic Critical Illness and Mortality Following Injury. J Trauma Acute Care Surg. 2023 Oct 26. View in PubMed
    3. Walborn AT, Heath A, Neal MD, Zarychanski R, Kornblith LZ, Hunt BJ, Castellucci LA, Hochman JS, Lawler PR, Paul JD. Effects of inflammation on thrombosis and outcomes in COVID-19: secondary analysis of the ATTACC/ACTIV-4a trial. Res Pract Thromb Haemost. 2023 Oct; 7(7):102203. View in PubMed
    4. Smilowitz NR, Hade EM, Kornblith LZ, Castellucci LA, Cushman M, Farkouh M, Gong MN, Heath A, Hunt BJ, Kim KS, Kindzelski A, Lawler P, Leaf DE, Goligher E, Leifer ES, McVerry BJ, Reynolds HR, Zarychanski R, Hochman JS, Neal MD, Berger JS. Effect of therapeutic-dose heparin on severe acute kidney injury and death in noncritically ill patients hospitalized for COVID-19: a prespecified secondary analysis of the ACTIV4a and ATTACC randomized trial. Res Pract Thromb Haemost. 2023 Aug; 7(6):102167. View in PubMed
    5. Solomon SD, Lowenstein CJ, Bhatt AS, Peikert A, Vardeny O, Kosiborod MN, Berger JS, Reynolds HR, Mavromichalis S, Barytol A, Althouse AD, Luther JF, Leifer ES, Kindzelski AL, Cushman M, Gong MN, Kornblith LZ, Khatri P, Kim KS, Baumann Kreuziger L, Wahid L, Kirwan BA, Geraci MW, Neal MD, Hochman JS, ACTIV4a Investigators. Effect of the P-Selectin Inhibitor Crizanlizumab on Survival Free of Organ Support in Patients Hospitalized for COVID-19: A Randomized Controlled Trial. Circulation. 2023 08; 148(5):381-390. View in PubMed
    6. View All Publications
    1. Diane A. Schwartz, Lucy Z. Kornblith, John B. Holcomb, Mitchell Jay Cohen. "Chapter 128. Multitrauma Derangement in Hemostasis and Thrombosis." In: Marder et al: Hemostasis and Thrombosis: Basic Principles and Clinical Practice, 6th eds. 2013
    2. Rochelle Dicker, Lucy Z. Kornblith. "Chapter 26. Acute Abdominal Pain." In: Vincent et al: Textbook of Critical Care, 7th eds. 2017
    3. Anamaria J. Robles, Lucy Z. Kornblith. "Coagulopathy in Trauma". In: Dynamed Plus, 2017 Zachary Matthay, Lucy Z. Kornblith. "Platelets." In: Trauma Induced Coagulopathy, 2nd eds. 2019
    4. Zachary Matthay, Lucy Z. Kornblith. "Platelet Contributions to Trauma Induced Coagulopathy: Updates in Post-injury Platelet Biology, Platelet Transfusions, and Emerging Platelet Based Hemostatic Agents." Hemostasis: Current Trauma Reports. 2019
    5. Zachary Matthay, Lucy Z. Kornblith. "Platelet Imaging." IntechOpen. http://mts.intechopen.com/articles/show/title/platelet-imaging. 2020
    6. Woon Cho Kim, Lucy Z. Kornblith "Injuries to the Liver and Biliary Tract." Blumgart's Surgery of the Liver, Biliary Tract and Pancreas, 7th Ed. 2020
    7. Zachary Matthay, Lucy Z. Kornblith. "Coagulopathy in Trauma". In: Dynamed Plus, 2020
    8. Lucy Z. Kornblith. "Doing Research at a University-Based Institution." Navigating Surgical Critical Care Fellowship Successfully and Beyond. Surgical Critical Care Fellow Handbook. November 2022
    9. Starr N, Matthay Z, Fields A, Neal M, Kornblith L. "Platelet Transfusion for Trauma Resuscitation." Current Trauma Reports. 2020
    10. David Efron, Matthew Benns, Lucy Kornblith. "Esophageal Emergencies." AAST/ESTES Emergency Surgery Course Handbook. 2022
    11. Kent Garber, Lucy Z. Kornblith. "Acute Respiratory Distress Syndrome." Clinical Scenarios in Surgery, 3rd Ed. 2023
    View all

     

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